Anti-MDR1 antibody
Specifications
| Product Cat#: | AB-06-2840 |
| Product type: | Primary antibody |
| Antigen: | MDR1 |
| Immunogen: | Mdr of hamster origin |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:10-1:200); Immunoprecipitation(1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) ); Immunohistochemistry (1:10-1:200); Immunofluorescence(1:10-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (1G6) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | ABC20 antibody |
| ABCB1 antibody | |
| ATP binding cassette, sub family B (MDR/TAP), member 1 antibody | |
| ATP-binding cassette sub-family B member 1 antibody | |
| CD243 antibody | |
| CLCS antibody | |
| Colchicin sensitivity antibody | |
| Doxorubicin resistance antibody | |
| GP170 antibody | |
| MDR1 antibody | |
| MDR1_HUMAN antibody | |
| Multidrug resistance 1 antibody | |
| Multidrug resistance protein 1 antibody | |
| P glycoprotein 1 antibody | |
| P gp antibody | |
| P-glycoprotein 1 antibody | |
| PGY1 antibody |
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Target information
Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218).
Provider
Erpantech Laboratory