Anti-MCM2 antibody
Specifications
| Product Cat#: | AB-06-2830 |
| Product type: | Primary antibody |
| Antigen: | MCM2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Immunohistochemistry (1:100-1:500); Immunocytochemistry (1:100-1:500); Western Blot (1:500-1:1000); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (C5-E7) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | BM28 antibody |
| CCNL 1 antibody | |
| CCNL1 antibody | |
| CDC like 1 antibody | |
| cdc19 antibody | |
| CDCL 1 antibody | |
| CDCL1 antibody | |
| Cell devision cycle like 1 antibody | |
| Cyclin like 1 antibody | |
| D3S3194 antibody | |
| DNA replication licensing factor MCM2 antibody | |
| KIAA0030 antibody | |
| MCM 2 antibody | |
| MCM2 antibody | |
| MCM2 minichromosome maintenance deficient 2 mitotin antibody | |
| MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody | |
| MCM2 minichromosome maintenance deficient 2, mitotin antibody | |
| MCM2_HUMAN antibody | |
| MGC10606 antibody | |
| Minichromosome maintenance complex component 2 antibody | |
| Minichromosome maintenance deficient 2 (mitotin) antibody | |
| Minichromosome maintenance deficient 2 mitotin antibody | |
| Minichromosome maintenance protein 2 antibody | |
| Minichromosome maintenance protein 2 homolog antibody | |
| Mitotin antibody | |
| Nuclear protein BM28 antibody | |
| OTTHUMP00000216047 antibody |
Target information
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ‘once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis.
Provider
Erpantech Laboratory