Anti-LRRC33 antibody
Specifications
| Product Cat#: | AB-06-2741 |
| Product type: | Primary antibody |
| Antigen: | LRRC33 |
| Immunogen: | KLH conjugated synthetic peptide derived from human LRRC33 501-600/692 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunofluorescence (1:100-1:500); Immunocytochemistry (1:100-1:500) |
| Reactivity: | Human, Mouse, Rat, Rabbit |
| Clonality (clone number): | Polyclonal |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | ELLP3030 |
| GARPL1 | |
| NRROS_HUMAN | |
| Leucine rich repeat containing protein 33 | |
| Lrcc33 |
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Target information
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system (By similarity). Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1 (By similarity).
Provider
Erpantech Laboratory
