Anti-Langerin antibody
Specifications
| Product Cat#: | AB-06-2670 |
| Product type: | Primary antibody |
| Antigen: | Langerin |
| Immunogen: | KLH conjugated synthetic peptide derived from human CD207 161-260/328 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | C-type lectin domain family 4 member K |
| CD207 antigen, langerin | |
| C type lectin domain family 4 member K | |
| CD 207 | |
| CD207 | |
| CD207 antigen | |
| CD207 molecule | |
| CLEC 4K | |
| CLEC4K | |
| Langerhans cell specific c type lectin | |
| RGD1565913 |
Target information
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Provider
Erpantech Laboratory
