Anti-KMT6/EZH2 antibody
Specifications
| Product Cat#: | AB-06-2637 |
| Product type: | Primary antibody |
| Antigen: | KMT6/EZH2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:2000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:50-1:200); Immunofluorescence |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JJ089-9) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Enhancer of Zeste 2 antibody |
| enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit antibody | |
| Enhancer of Zeste Homolog 2 (Drosophila) antibody | |
| Enhancer of Zeste Homolog 2 antibody | |
| Enhancer of Zeste, Drosophila, Homolog 2 antibody | |
| ENX 1 antibody | |
| Enx 1h antibody | |
| ENX-1 antibody | |
| ENX1 antibody | |
| Enx1h antibody | |
| EZH 2 antibody | |
| EZH1 antibody | |
| EZH2 antibody | |
| EZH2_HUMAN antibody | |
| EZH2b antibody | |
| Histone-lysine N-Methyltransferase EZH2 antibody | |
| KMT 6 antibody | |
| KMT6 antibody | |
| KMT6A antibody | |
| Lysine N-Methyltransferase 6 antibody | |
| MGC9169 antibody | |
| WVS antibody |
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Target information
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates ‘Lys-9’ (H3K9me) and ‘Lys-27’ (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate ‘Lys-27’ of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2 (PubMed:22323599, PubMed:30923826).
Provider
Erpantech Laboratory
