Anti-KLHL22 antibody
Specifications
| Product Cat#: | AB-06-2629 |
| Product type: | Primary antibody |
| Antigen: | KLHL22 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500); Immunocytochemistry (1:100-1:500) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (A6-B10) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | 2610318I18Rik antibody |
| kelch-Like 22 antibody | |
| kelch-Like Family Member 22 antibody | |
| Kelch-Like Protein 22 antibody | |
| KELCHL antibody | |
| KLH22_HUMAN antibody | |
| Klhl22 antibody | |
| RGD1306288 antibody |
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Target information
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation.
Provider
Erpantech Laboratory