Anti-KLHL12 antibody
Specifications
| Product Cat#: | AB-06-2624 |
| Product type: | Primary antibody |
| Antigen: | KLHL12 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:1000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (B1-G2) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | C3IP1 antibody |
| CUL3 Interacting Protein 1 antibody | |
| CUL3-Interacting Protein 1 antibody | |
| DKIR antibody | |
| DKIR homolog antibody | |
| FLJ27152 antibody | |
| hDKIR antibody | |
| Kelch Like 12 (Drosophila) antibody | |
| Kelch Like 12 antibody | |
| Kelch Like 12 Variant antibody | |
| Kelch Like protein 12 antibody | |
| Kelch Like protein C3IP1 antibody | |
| kelch-Like Family Member 12 antibody | |
| Kelch-Like Protein 12 antibody | |
| KLH12_HUMAN antibody | |
| KLHL 12 antibody | |
| Klhl12 antibody | |
| OTTHUMP00000038799 antibody |
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Target information
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport (PubMed:22358839, PubMed:27565346). The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B) (PubMed:22358839, PubMed:27565346).
Provider
Erpantech Laboratory