Anti-Kir6.2 antibody
Specifications
| Product Cat#: | AB-06-2606 |
| Product type: | Primary antibody |
| Antigen: | Kir6.2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Kir62 301-390/390 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunocytochemistry (1:50-1:200); Immunofluorescence (1:100-1:500); Flow Cytometry (3ug/test) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | ATP Sensitive Inward Rectifier Potassium Channel 11 |
| Beta Cell Inward Rectifier Subunit | |
| mBIR | |
| BIR | |
| HHF 2 | |
| HHF2 | |
| IKATP | |
| Inward Rectifier K (+) Channel Inwardly Rectifying Potassium Channel KIR6.2 | |
| IRK 11 | |
| IRK11 | |
| KCNJ11 | |
| Kir 6.2 | |
| MGC133230 | |
| PHHI | |
| Potassium Channel, Inwardly Rectifying Subfamily J Member 11 | |
| Potassium Inwardly Rectifying Channel J11 | |
| TNDM 3 | |
| TNDM3 | |
| IRK11_HUMAN |
Target information
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Provider
Erpantech Laboratory
