Anti-KDM6A antibody
Specifications
| Product Cat#: | AB-06-2576 |
| Product type: | Primary antibody |
| Antigen: | KDM6A |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | bA386N14.2 (Ubiquitously Transcribed X Chromosome Tetratricopeptide Repeat Protein (UTX) antibody |
| bA386N14.2 antibody | |
| bA386N14.2 Ubiquitously Transcribed X Chromosome Tetratricopeptide Repeat Protein UTX antibody | |
| DKFZp686A03225 antibody | |
| Histone Demethylase UTX antibody | |
| KABUK2 antibody | |
| Kdm6a antibody | |
| KDM6A_HUMAN antibody | |
| Lysine (K) Specific Demethylase 6A antibody | |
| Lysine K Specific Demethylase 6A antibody | |
| Lysine Specific Demethylase 6A Ubiquitously Transcribed Tetratricopeptide Repeat Gene X Chromosome antibody | |
| Lysine-Specific Demethylase 6A antibody | |
| MGC141941 antibody | |
| Ubiquitously Transcribed Tetratricopeptide Repeat X chromosome antibody | |
| Ubiquitously Transcribed Tetratricopeptide Repeat Protein X Linked antibody | |
| Ubiquitously Transcribed TPR Gene on the X Chromosome antibody | |
| Ubiquitously Transcribed TPR Protein on the X Chromosome antibod |
Target information
Histone demethylase that specifically demethylates ‘Lys-27’ of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 ‘Lys-27’ (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of ‘Lys-27’ of histone H3 is concomitant with methylation of ‘Lys-4’ of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression (By similarity).
Provider
Erpantech Laboratory
