Anti-KDM4A antibody
Specifications
| Product Cat#: | AB-06-2571 |
| Product type: | Primary antibody |
| Antigen: | KDM4A |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Immunocytochemistry (1:50-1:200); Immunohistochemistry (1:50-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (E7-H1) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | JHDM3A antibody |
| JmjC Domain Containing Histone Demethylation Protein 3A antibody | |
| JmjC Domain-Containing Histone Demethylation Protein 3A antibody | |
| JMJD2 antibody | |
| JMJD2A antibody | |
| jumonji C domain Containing Histone Demethylase 3A antibody | |
| Jumonji Domain Containing 2 antibody | |
| Jumonji Domain Containing 2A antibody | |
| Jumonji Domain Containing Protein 2A antibody | |
| Jumonji Domain-Containing Protein 2A antibody | |
| KDM4A antibody | |
| KDM4A_HUMAN antibody | |
| KIAA0677 antibody | |
| Lysine (K) Specific Demethylase 4A antibody | |
| Lysine-Specific Demethylase 4A antibody | |
| TDRD14A antibody | |
| Tudor Domain Containing 14A antibody |
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Target information
Histone demethylase that specifically demethylates ‘Lys-9’ and ‘Lys-36’ residues of histone H3, thereby playing a central role in histone code (PubMed:26741168). Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’ nor H4 ‘Lys-20’. Demethylates trimethylated H3 ‘Lys-9’ and H3 ‘Lys-36’ residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Provider
Erpantech Laboratory
