Anti-KBTBD8 antibody
Specifications
| Product Cat#: | AB-06-2553 |
| Product type: | Primary antibody |
| Antigen: | KBTBD8 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1:50-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (6G-8A) |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH7.4), 1% BSA, 50% Glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AU040152 antibody |
| FLJ57592 antibody | |
| KBTB8_HUMAN antibody | |
| Kbtbd8 antibody | |
| Kelch Repeat and BTB (POZ) Domain Containing 8 antibody | |
| Kelch Repeat and BTB Domain Containing Protein 8 antibody | |
| Kelch Repeat and BTB Domain-Containing Protein 8 antibody | |
| KIAA1842 antibody | |
| MGC91215 antibody | |
| mKIAA1842 antibody | |
| OTTHUMP00000213470 antibody | |
| RGD1563166 antibody | |
| SSEC 51 antibody | |
| SSEC51 antibody | |
| T cell Activation Kelch Repeat Protein antibody | |
| T-cell Activation Kelch Repeat Protein antibody | |
| TA KRP antibody | |
| TA-KRP antibody | |
| Takrp antibody |
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Target information
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).
Provider
Erpantech Laboratory