Anti-IQGAP1 Antibody
Specifications
| Product Cat#: | AB-06-2495 |
| Product type: | Primary antibody |
| Antigen: | IQGAP1 |
| Immunogen: | Recombinant protein corresponding to N-terminal human IQGAP1. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunocytochemistry (1:80-1:200); Immunofluorescence (1:80-1:200); Immunohistochemistry (1:80-1:200); Flow Cytometry (1:80-1:200) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal(JG38-74) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | HUMORFA01 antibody |
| IQ motif containing GTPase activating protein 1 antibody | |
| IQGA1_HUMAN antibody | |
| Iqgap1 antibody | |
| KIAA0051 antibody | |
| p195 antibody | |
| Ras GTPase activating like protein 1 antibody | |
| Ras GTPase-activating-like protein IQGAP1 antibody | |
| RasGAP-like with IQ motifs antibody | |
| SAR1 antibody |
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Target information
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).
Provider
Erpantech Laboratory
