Anti-Integrin Beta 4 Antibody
Specifications
| Product Cat#: | AB-06-2477 |
| Product type: | Primary antibody |
| Antigen: | Integrin beta 4 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:80-1:200) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal(JM11-06) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 104 antibody |
| CD104 antibody | |
| CD104 antigen antibody | |
| gp150 antibody | |
| Integrin beta 4 subunit antibody | |
| Integrin beta-4 antibody | |
| ITB4_HUMAN antibody | |
| ITG B4 antibody | |
| ITGB 4 antibody | |
| Itgb4 antibody |
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Target information
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
Provider
Erpantech Laboratory