Anti-Integrin Alpha 6 Antibody
Specifications
| Product Cat#: | AB-06-2470 |
| Product type: | Primary antibody |
| Antigen: | Integrin alpha 6 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1500); Immunohistochemistry (1:80-1:200) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal(SR45-00) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Alpha6p antibody |
| CD49 antigen-like family member F antibody | |
| CD49f antibody | |
| Integrin alpha6B antibody | |
| Integrin, alpha 6 antibody | |
| ITA6_HUMAN antibody | |
| ITGA6 antibody | |
| ITGA6B antibody | |
| Processed integrin alpha-6 antibody | |
| VLA 6 antibody | |
| VLA-6 antibody |
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Target information
Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
Provider
Erpantech Laboratory
