Anti-Integrin alpha-3 Mouse Monoclonal antibody
Specifications
| Product Cat#: | AB-06-4959 |
| Product type: | Primary antibody |
| Antigen: | Integrin alpha-3 |
| Immunogen: | Recombinant protein within Human Integrin alpha-3 aa 51-250/1,051. |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, A7H2 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH 7.4), 0.05% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/mL |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AA407068 antibody |
| Antigen identified by monoclonal antibody J143 antibody | |
| CD49 antigen like family member C antibody | |
| CD49 antigen-like family member C antibody | |
| CD49c antibody | |
| CD49c antigen antibody | |
| FLJ34631 antibody | |
| FLJ34704 antibody | |
| FRP 2 antibody | |
| FRP-2 antibody | |
| FRP2 antibody | |
| Galactoprotein B3 antibody | |
| GAP B3 antibody | |
| GAPB3 antibody | |
| Integrin alpha 3 antibody | |
| Integrin alpha-3 light chain antibody | |
| Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody | |
| ITA3_HUMAN antibody | |
| ITGA 3 antibody | |
| Itga3 antibody | |
| MSK18 antibody | |
| VCA 2 antibody | |
| VCA2 antibody | |
| Very late activation protein 3 receptor alpha 3 subunit antibody | |
| VL3A antibody | |
| VLA 3 alpha chain antibody | |
| VLA 3 subunit alpha antibody | |
| VLA-3 subunit alpha antibody | |
| VLA3a antibody | |
| Integrinalpha-3 |
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Target information
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
(Microbial infection) Integrin ITGA3:ITGB1 may act as a receptor for R.delemar CotH7 in alveolar epithelial cells, which may be an early step in pulmonary mucormycosis disease progression.
Provider
Erpantech Laboratory