Anti-IL10RB antibody
Specifications
| Product Cat#: | AB-06-2387 |
| Product type: | Primary antibody |
| Antigen: | IL10RB |
| Immunogen: | KLH conjugated synthetic peptide derived from human IL-10RB 21-120/325 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000) |
| Reactivity: | Mouse, Rat , Dog, Pig, Cow, Horse, Rabbit and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Cd210 |
| CDw210b | |
| CRF2 4 | |
| CRF2-4 | |
| CRFB4 | |
| Cytokine receptor class II | |
| Cytokine receptor class II CRF2 4 | |
| Cytokine receptor class-II member 4 | |
| Cytokine receptor family 2 member 4 | |
| Cytokine receptor family II member 4 | |
| D21S58 | |
| D21S66 | |
| I10R2_HUMAN | |
| IL-10 receptor subunit beta | |
| IL-10R subunit 2 | |
| IL-10R subunit beta | |
| IL-10R2 | |
| IL-10RB | |
| IL10R2 | |
| IL10RB | |
| Interleukin 10 receptor beta | |
| Interleukin-10 receptor subunit 2 |
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Target information
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
Provider
Erpantech Laboratory
