Anti-IKB Beta antibody
Specifications
| Product Cat#: | AB-06-2376 |
| Product type: | Primary antibody |
| Antigen: | IKB beta |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunocytochemistry (1:80-1:200); Immunohistochemistry (1:80-1:200); Immunoprecipitation |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (SN0648) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | I kappa B beta antibody |
| I-kappa-B-beta antibody | |
| IkappaBbeta antibody | |
| IKB beta antibody | |
| IkB-B antibody | |
| IkB-beta antibody | |
| IKBB antibody | |
| IKBB_HUMAN antibody | |
| IkBbeta antibody | |
| NF kappa BIB antibody | |
| NF-kappa-B inhibitor beta antibody | |
| NF-kappa-BIB antibody | |
| Nfkbib antibody | |
| Thyroid receptor interacting protein 9 antibody | |
| Thyroid receptor-interacting protein 9 antibody | |
| TR interacting protein 9 antibody | |
| TR-interacting protein 9 antibody | |
| TRIP-9 antibody | |
| TRIP9 antibody |
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Target information
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Provider
Erpantech Laboratory