Anti-Ikaros antibody
Specifications
| Product Cat#: | AB-06-2374 |
| Product type: | Primary antibody |
| Antigen: | Ikaros |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:80-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JB50-38) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CLL associated antigen KW 6 antibody |
| DNA-binding protein Ikaros antibody | |
| HIk 1 antibody | |
| Hs.54452 antibody | |
| IK1 antibody | |
| Ikaros (zinc finger protein) antibody | |
| IKAROS antibody | |
| IKAROS family zinc finger 1 (Ikaros) antibody | |
| Ikaros family zinc finger protein 1 antibody | |
| Ikzf1 antibody | |
| IKZF1_HUMAN antibody | |
| LYF1 antibody | |
| Lymphoid transcription factor LyF-1 antibody | |
| PRO0758 antibody | |
| Zinc finger protein subfamily 1A 1 (Ikaros) antibody | |
| Zinc finger protein subfamily 1A 1 antibody | |
| Zinc finger protein, subfamily 1A, member 1 antibody | |
| ZNFN1A1 antibody |
Target information
Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
Provider
Erpantech Laboratory