Anti-IkappaB Alpha antibody
Specifications
| Product Cat#: | AB-06-2373 |
| Product type: | Primary antibody |
| Antigen: | IkappaB alpha |
| Immunogen: | A synthetic peptide corresponding to human IkappaB-alpha was used as immunogen. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:50-1:100); Immunocytochemistry (1:80-1:200); Immunoprecipitation |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (1E3) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | I kappa B alpha antibody |
| I-kappa-B-alpha antibody | |
| IkappaBalpha antibody | |
| IkB-alpha antibody | |
| IKBA antibody | |
| IKBA_HUMAN antibody | |
| IKBalpha antibody | |
| MAD 3 antibody | |
| MAD3 antibody | |
| Major histocompatibility complex enhancer-binding protein MAD3 antibody | |
| NF kappa B inhibitor alpha antibody | |
| NF-kappa-B inhibitor alpha antibody | |
| NFKBI antibody | |
| NFKBIA antibody | |
| Nuclear factor of kappa light chain gene enhancer in B cells antibody | |
| Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor |
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Target information
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Provider
Erpantech Laboratory
