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Anti-IgA antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-2355
Anti-IgA antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-2355
Product type: Primary antibody
Antigen: IgA
Immunogen: Native protein
Species immunized: Mouse
Isotype: IgG2a
Applications: Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200); ELISA
Reactivity: Human
Clonality (clone number): Monoclonal(5-C3)
Form: Liquid
Buffer: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 2 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names:
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Target information

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).

Provider

Erpantech Laboratory

download

MSDS-AB-06-2355.pdf (134 downloads )