Anti-IFNAR1 antibody
Specifications
| Product Cat#: | AB-06-2348 |
| Product type: | Primary antibody |
| Antigen: | IFNAR1 |
| Immunogen: | Synthetic peptide within Human IFNAR1 aa 508-557 / 557. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:80-1:200); Flow Cytometry (1:80-1:200); Immunoprecipitation |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (SR45-08) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Alpha type antiviral protein antibody |
| AVP antibody | |
| Beta type antiviral protein antibody | |
| CRF2-1 antibody | |
| Cytokine receptor class-II member 1 antibody | |
| Cytokine receptor family 2 member 1 antibody | |
| IFN alpha REC antibody | |
| IFN alpha receptor antibody | |
| IFN alpha/beta Receptor alpha antibody | |
| IFN beta receptor antibody | |
| IFN-alpha/beta receptor 1 antibody | |
| IFN-R-1 antibody | |
| IFNAR antibody | |
| Ifnar1 antibody | |
| IFNBR antibody | |
| IFRC antibody | |
| INAR1_HUMAN antibody | |
| Interferon (alpha beta and omega) receptor 1 antibody | |
| Interferon alpha/beta receptor 1 antibody | |
| Interferon alpha/beta receptor alpha chain antibody | |
| Interferon beta receptor 1 antibody | |
| Type I interferon receptor 1 antibody |
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Target information
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
Provider
Erpantech Laboratory
