Anti-ID2 antibody
Specifications
| Product Cat#: | AB-06-2336 |
| Product type: | Primary antibody |
| Antigen: | ID2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:10000); Immunocytochemistry (1:80-1:200); Immunohistochemistry (1:80-1:200) |
| Reactivity: | Mouse and Human |
| Clonality (clone number): | Monoclonal (A4-D4) |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein Aaffinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | bHLHb26 antibody |
| Cell growth inhibiting gene 8 antibody | |
| class B basic helix loop helix protein 26 antibody | |
| Class B basic helix-loop-helix protein 26 antibody | |
| DNA binding protein inhibitor ID 2 antibody | |
| DNA binding protein inhibitor ID2 antibody | |
| DNA-binding protein inhibitor ID-2 antibody | |
| GIG 8 antibody | |
| GIG8 antibody | |
| Helix loop helix protein ID2 antibody | |
| ID2 antibody | |
| VID2_HUMAN antibody | |
| ID2A antibody | |
| ID2H antibody | |
| Inhibitor of differentiation 2 antibody | |
| Inhibitor of DNA binding 2 antibody | |
| Inhibitor of DNA binding 2, dominant negative helix loop helix protein antibody |
Target information
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK -ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
Provider
Erpantech Laboratory
