Anti-ICAM1 antibody
Specifications
| Product Cat#: | AB-06-2325 |
| Product type: | Primary antibody |
| Antigen: | ICAM1 |
| Immunogen: | This antibody is produced by immunizing mice with a synthetic peptide (KLHcoupled) corresponding to a region of human ICAM1. |
| Species immunized: | Mouse |
| Isotype: | IgG1a |
| Applications: | Western Blot (1:2500-1:4500); Immunocytochemistry (1:800-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal(F11-A4) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
| Concentration: | 2 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BB2 antibody |
| BB 2 antibody | |
| BB2 antibody | |
| CD 54 antibody | |
| CD_antigen=CD54 antibody | |
| CD54 antibody | |
| Cell surface glycoprotein P3.58 antibody | |
| Human rhinovirus receptor antibody | |
| ICAM 1 antibody | |
| ICAM-1 antibody | |
| ICAM1 antibody | |
| ICAM1_HUMAN antibody | |
| intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody | |
| Intercellular adhesion molecule 1 antibody | |
| Major group rhinovirus receptor antibody | |
| MALA 2 antibody | |
| MALA2 antibody | |
| MyD 10 antibody | |
| MyD10 antibody | |
| P3.58 antibody |
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Target information
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins.(Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins.(Microbial infection) Upon Kaposi’s sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Provider
Erpantech Laboratory
