Anti-Human IgG4 antibody
Specifications
| Product Cat#: | AB-06-2306 |
| Product type: | Primary antibody |
| Antigen: | Human IgG4 |
| Immunogen: | Human IgG4 |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | ELISA (1:50-3000) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, 2G1 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Ig gamma 4 chain C region antibody |
| IGHG4 antibody | |
| Immunoglobulin heavy chain constant region gamma 4 antibody | |
| Immunoglobulin heavy constant gamma 4 (G4m marker) antibody | |
| MGC117419 antibody |
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Target information
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
Provider
Erpantech Laboratory
