Anti-HSP105 antibody
Specifications
| Product Cat#: | AB-06-2265 |
| Product type: | Primary antibody |
| Antigen: | HSP105 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunoprecipitation; Immunofluorescence; Western Blot (1:800-1:2000); Immunohistochemistry (1:60-1:200); Immunocytochemistry (1:60-1:200); |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal （SD85-06） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Antigen NY CO 25 antibody |
| Antigen NY-CO-25 antibody | |
| DKFZp686M05240 antibody | |
| Heat shock 105kD alpha antibody | |
| Heat shock 105kD antibody | |
| Heat shock 105kD beta antibody | |
| Heat shock 105kDa protein 1 antibody | |
| Heat shock 105kDa protein antibody | |
| Heat shock 105kDa/110kDa protein 1 antibody | |
| Heat shock 110 kDa protein antibody | |
| Heat shock 110kDa protein antibody | |
| Heat shock protein 105 kDa antibody | |
| HS105_HUMAN antibody | |
| HSP105 antibody | |
| HSP105A antibody | |
| HSP105B antibody | |
| HSP110 antibody | |
| HSPH 1 antibody | |
| Hsph1 antibody | |
| KIAA0201 antibody | |
| NY CO 25 antibody |
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Target information
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
Provider
Erpantech Laboratory