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Anti-HIPK1 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-2167
Anti-HIPK1 antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-2167
Product type: Primary antibody
Antigen: HIPK1
Immunogen: KLH conjugated synthetic peptide derived from human HIPK1 1-100/1210
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:600-1:2000); Immunohistochemistry-Paraffin (1:500-1:800)
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Macaque Monkey
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4),with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Hipk 1
Hipk1
HIPK1_HUMAN
Homeodomain interacting protein kinase 1
Homeodomain interacting protein kinase 1 like protein
Homeodomain-interacting protein kinase 1
Myak
Nbak 2
Nbak2
Nuclear body associated kinase 2
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Target information

Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

Provider

Erpantech Laboratory

download

MSDS-AB-06-2167.pdf (53 downloads )