Anti-Hint1 antibody
Specifications
| Product Cat#: | AB-06-2163 |
| Product type: | Primary antibody |
| Antigen: | Hint1 |
| Immunogen: | Amino acids 8-47 mapping near the N-terminus of Hint 1 of human origin. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:200-1:1000); Immunoprecipitation:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate); Immunofluorescence(1:50-1:500) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (4G12） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Adenosine 5' monophosphoramidase antibody |
| Adenosine 5"-monophosphoramidase antibody | |
| HINT 1 antibody | |
| HINT1 antibody | |
| HINT1_HUMAN antibody | |
| Histidine triad nucleotide binding protein 1 antibody | |
| Histidine triad nucleotide-binding protein 1 antibody | |
| PKCI 1 antibody | |
| PKCI-1 antibody | |
| PKCI1 antibody | |
| PRKCNH1 antibody | |
| Protein kinase C inhibitor 1 antibody | |
| Protein kinase C interacting protein 1 antibody | |
| Protein kinase C-interacting protein 1 antibody |
Target information
Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5’monophosphoramidate (AMP-NH2), adenosine 5’monophosphomorpholidate (AMP-morpholidate) and guanosine 5’monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5′-O-phosphorothioate and guanosine 5′-O-phosphorothioate to the corresponding nucleoside 5′-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Provider
Erpantech Laboratory
