Anti-HIF-2 Alpha antibody
Specifications
| Product Cat#: | AB-06-2161 |
| Product type: | Primary antibody |
| Antigen: | HIF-2 alpha |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (JB24-42） |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Basic helix loop helix PAS protein MOP2 antibody |
| Basic-helix-loop-helix-PAS protein MOP2 antibody | |
| BHLHe73 antibody | |
| Class E basic helix-loop-helix protein 73 antibody | |
| ECYT4 antibody | |
| Endothelial PAS domain containing protein 1 antibody | |
| Endothelial pas domain protein 1 antibody | |
| Endothelial PAS domain-containing protein 1 antibody | |
| EPAS 1 antibody | |
| EPAS-1 antibody | |
| EPAS1 antibody | |
| EPAS1_HUMAN antibody | |
| HIF 1 alpha like factor antibody | |
| HIF 2 alpha antibody | |
| HIF-1-alpha-like factor antibody | |
| HIF-2-alpha antibody | |
| HIF2-alpha antibody | |
| HIF2A antibody | |
| HLF antibody | |
| Hypoxia inducible factor 2 alpha antibody | |
| Hypoxia inducible factor 2 alpha subunit antibody | |
| Hypoxia-inducible factor 2-alpha antibody | |
| Member of PAS protein 2 antibody | |
| Member of pas superfamily 2 antibody | |
| MOP 2 antibody | |
| MOP2 antibody | |
| PAS domain-containing protein 2 antibody | |
| PASD2 antibody |
Target information
Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5′-TACGTG-3′ within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
Provider
Erpantech Laboratory
