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Anti-HIF-1 Beta antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-2159
Anti-HIF-1 Beta antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-2159
Product type: Primary antibody
Antigen: HIF-1 beta
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:800-1:2000); Immunohistochemistry (1:100-1:200)
Reactivity: Human
Clonality (clone number): Monoclonal (ST05-25)
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: arnT antibody
ARNT protein antibody
ARNT_HUMAN antibody
Aryl hydrocarbon receptor nuclear translocator antibody
BHLHe2 antibody
Class E basic helix-loop-helix protein 2 antibody
Dioxin receptor antibody
Dioxin receptor nuclear translocator antibody
Drnt antibody
HIF 1 beta antibody
HIF 1beta antibody
HIF-1-beta antibody
HIF1-beta antibody
HIF1B antibody
HIF1beta antibody
Hypoxia Inducible Factor 1 antibody
Hypoxia inducible factor 1 beta antibody
Hypoxia-inducible factor 1-beta antibody
nuclear translocator antibody
Tango antibody
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Target information

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5′-TACGTG-3′ within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5′-TGCGTG-3′ within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).

Provider

Erpantech Laboratory

download

MSDS-AB-06-2159.pdf (40 downloads)