Anti-HES6 antibody
Specifications
| Product Cat#: | AB-06-2144 |
| Product type: | Primary antibody |
| Antigen: | HES6 |
| Immunogen: | KLH conjugated synthetic peptide derived from human HES6 1-80/224 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000） |
| Reactivity: | Human, Mouse, Rat, Pig, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BHLHb41 |
| BHLHb41 | |
| BHLHc23 | |
| C HAIRY1 | |
| Class B basic helix-loop-helix protein 41 | |
| Hairy and enhancer of split 6 | |
| HES 6 | |
| Transcription cofactor HES6 |
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Target information
Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation .
Provider
Erpantech Laboratory
