Anti-HDAC10 antibody
Specifications
| Product Cat#: | AB-06-2105 |
| Product type: | Primary antibody |
| Antigen: | HDAC10 |
| Immunogen: | Purified recombinant fragment of human HDAC10 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG2a |
| Applications: | Western Blot (1:200-1:2000); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (8B-6B) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | ProA affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DKFZP761B039 antibody |
| HD 10 antibody | |
| HD10 antibody | |
| HDA10_HUMAN antibody | |
| HDAC 10 antibody | |
| Hdac10 antibody | |
| Histone deacetylase 10 antibody | |
| MGC149722 antibody | |
| OTTHUMP00000028555 antibody |
Target information
Polyamine deacetylase (PDAC), which acts preferentially on N8-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954). Exhibits attenuated catalytic activity toward N1,N8-diacetylspermidine and very low activity, if any, toward N1-acetylspermidine (PubMed:28516954). Histone deacetylase activity has been observed in vitro (PubMed:11861901, PubMed:11726666, PubMed:11677242, PubMed:11739383). Has also been shown to be involved in MSH2 deacetylation (PubMed:26221039). The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak (PubMed:28516954). May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells (PubMed:23801752, PubMed:29968769). May play a role in homologous recombination (PubMed:21247901). May promote DNA mismatch repair (PubMed:26221039).
Provider
Erpantech Laboratory
