Anti-Haptoglobin antibody
Specifications
| Product Cat#: | AB-06-2089 |
| Product type: | Primary antibody |
| Immunogen: | Native protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot; Immunohistochemistry; ELISA |
| Clonality (clone number): | Monoclonal (A10-F5) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: |
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Target information
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Provider
Erpantech Laboratory