Anti-GTP Cyclohydrolase 1 antibody
Specifications
| Product Cat#: | AB-06-2072 |
| Product type: | Primary antibody |
| Antigen: | GTP Cyclohydrolase 1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GTP-CH-1 34-110/250 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | GTP-CH-1 |
| DYT 5 | |
| DYT5 | |
| GCH 1 | |
| GCH | |
| GCH1 | |
| GTP CH 1 | |
| GTP CH I | |
| GTP cyclohydrolase 1 (dopa responsive dystonia) | |
| GTP cyclohydrolase 1 | |
| GTP cyclohydrolase I | |
| GTPCH 1 | |
| GTPCH1 | |
| Guanosine 5' triphosphate cyclohydrolase I | |
| DYT14 | |
| DYT5a |
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Target information
Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.
Provider
Erpantech Laboratory
