Anti-GRB7 Antibody
Specifications
| Product Cat#: | AB-06-4937 |
| Product type: | Primary antibody |
| Antigen: | GRB7 |
| Immunogen: | Recombinant protein within human GRB7 aa 1-200/532. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:5000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCL buffer (pH7.4), 0.2% BSA, 50% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified. |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Conjugate: | Unconjugated |
| Alternative names: | B47 antibody |
| Epidermal growth factor receptor GRB 7 antibody | |
| Epidermal growth factor receptor GRB-7 antibody | |
| GRB7 adapter protein antibody | |
| GRB7 antibody | |
| GRB7_HUMAN antibody | |
| Growth factor receptor bound protein 7 antibody | |
| Growth factor receptor-bound protein 7 antibody | |
| OTTHUMP00000164349 antibody | |
| OTTHUMP00000164350 antibody | |
| OTTHUMP00000164351 antibody | |
| OTTHUMP00000164352 antibody |
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Target information
Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5’UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.
Provider
Erpantech Laboratory
