Anti-GPR49/LGR5 alpha/beta antibody
Specifications
| Product Cat#: | AB-06-2010 |
| Product type: | Primary antibody |
| Antigen: | GPR49/LGR5 alpha/beta |
| Immunogen: | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of LGR5. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:200) |
| Reactivity: | Human, mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | FEX antibody |
| G protein coupled receptor 49 antibody | |
| G protein coupled receptor 67 antibody | |
| g protein-coupled receptor fex antibody | |
| G-protein coupled receptor 49 antibody | |
| G-protein coupled receptor 67 antibody | |
| G-protein coupled receptor HG38 antibody | |
| GPR 49 antibody | |
| GPR 67 antibody | |
| GPR49 antibody | |
| GPR67 antibody | |
| GRP 49 antibody | |
| GRP49 antibody | |
| HG 38 antibody | |
| HG38 antibody | |
| Leucine rich repeat containing G protein coupled receptor 5 antibody | |
| Leucine-rich repeat-containing G-protein coupled receptor 5 antibody | |
| LGR 5 antibody | |
| LGR5 antibody | |
| LGR5_HUMAN antibody | |
| MGC117008 antibody |
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Target information
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
Provider
Erpantech Laboratory
