Anti-GPR30 antibody
Specifications
| Product Cat#: | AB-06-2006 |
| Product type: | Primary antibody |
| Antigen: | GPR30 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GPR30 251-375/375 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:400-1:800); Flow Cytometry (1) |
| Reactivity: | Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | G Protein Coupled Receptor 30 |
| G-protein coupled receptor 30 | |
| G-protein coupled estrogen receptor 1 | |
| Membrane estrogen receptor | |
| mER | |
| Chemokine receptor-like 2 | |
| IL8-related receptor DRY12 | |
| Flow-induced endothelial G-protein coupled receptor 1 | |
| FEG-1 | |
| Lymphocyte-derived G-protein coupled receptor | |
| LYGPR | |
| GPCR-BR | |
| CEPR | |
| CMKRL2 | |
| DRY12 |
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Target information
G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems.
Provider
Erpantech Laboratory
