Anti-GPR120 antibody
Specifications
| Product Cat#: | AB-06-1997 |
| Product type: | Primary antibody |
| Antigen: | GPR120 |
| Immunogen: | KLH conjugated synthetic peptide derived from human G protein coupled receptor 120 21-120/377 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | G protein coupled receptor 120 |
| GPCR GPR120 | |
| G protein coupled receptor 129 | |
| G protein coupled receptor GT01 | |
| G protein coupled receptor PGR 4 | |
| G protein coupled receptor PGR4 | |
| G-protein coupled receptor 120 | |
| G-protein coupled receptor 129 | |
| G-protein coupled receptor GT01 | |
| G-protein coupled receptor PGR4 | |
| GPR 120 | |
| GPR 129 | |
| GPR120 | |
| GPR129 | |
| GT01 | |
| HGNC:19345 | |
| MGC119984 | |
| O3FA1_HUMAN | |
| O3FAR1 | |
| Omega-3 fatty acid receptor 1 | |
| PGR 4 | |
| PGR4 |
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Target information
Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation
Provider
Erpantech Laboratory
