Anti-GOSR1 antibody
Specifications
| Product Cat#: | AB-06-1975 |
| Product type: | Primary antibody |
| Antigen: | GOSR1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GOSR1/GS28 151-250/250 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | 28 kDa cis Golgi SNARE p28 |
| 28 kDa Golgi SNARE protein | |
| Golgi SNAP receptor complex member 1 | |
| Golgi SNARE 28 kDa | |
| GOS28 | |
| GOS28/P28 | |
| GOSR1 | |
| GS25 | |
| Gs28 | |
| P28 |
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Target information
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Provider
Erpantech Laboratory
