Anti-GNL1 antibody
Specifications
| Product Cat#: | AB-07-2914 |
| Product type: | Primary antibody |
| Antigen: | GNL1 |
| Immunogen: | A synthetic peptide derived from human GNL1. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:3000); ELISA (1:20000) |
| Reactivity: | Mouse, Human, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | GTP-binding protein HSR1; guanine nucleotide binding protein-like 1; guanine nucleotide-binding protein-like 1; HSR1; HSR1 GTP-binding protein |
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Target information
Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of retrograde Golgi to endoplasmic reticulum trafficking but is also involved in the endocytosis process. Could function redundantly with GNOM. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the endocytosis of PIN2 from plasma membrane to endosomal compartments. Required for maintenance of endoplasmic reticulum morphology.
Provider
Erpantech Laboratory
