Anti-GLUR4 antibody
Specifications
| Product Cat#: | AB-06-1940 |
| Product type: | Primary antibody |
| Antigen: | GLUR4 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GLUR4 501-600/902 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Ionotropic Glutamate receptor 4 |
| AMPA 4 | |
| AMPA selective glutamate receptor 4 | |
| GluR 4 | |
| GluR D | |
| GLUR4 | |
| GLUR4C | |
| GLURD | |
| Glutamate receptor 4 | |
| Glutamate receptor ionotrophic AMPA 4 | |
| GRIA 4 | |
| GRIA4 |
Target information
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Provider
Erpantech Laboratory
