Anti-Glucagon Receptor antibody
Specifications
| Product Cat#: | AB-06-1926 |
| Product type: | Primary antibody |
| Antigen: | Glucagon Receptor |
| Immunogen: | KLH conjugated synthetic peptide derived from human Glucagon Receptor 11-110/477 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800); Flow Cytometry (1μg/Test) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Guinea Pig |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | GCGR |
| GGR | |
| GL R | |
| GL-R | |
| GLR | |
| GLR_HUMAN | |
| MGC138246 |
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Target information
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Provider
Erpantech Laboratory