Anti-Gliomedin antibody
Specifications
| Product Cat#: | AB-06-1917 |
| Product type: | Primary antibody |
| Antigen: | Gliomedin |
| Immunogen: | KLH conjugated synthetic peptide derived from human Gliomedin/COLM 365-460/551 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | CANCER RELATED GENE LIVER 2 |
| Cancer related gene-Liver 2 | |
| CLOM | |
| collomin | |
| Colm (gene name) | |
| COLM | |
| Colmedin | |
| CRG L2 | |
| FLJ23917 | |
| Gldn (gene name) | |
| UNC 112 |
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Target information
Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
Provider
Erpantech Laboratory
