Anti-GGT1 antibody
Specifications
| Product Cat#: | AB-06-1902 |
| Product type: | Primary antibody |
| Antigen: | GGT1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GGT1 351-460/569 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | CD224 |
| Gamma glutamyl transpeptidase | |
| Gamma glutamyltransferase 1 | |
| Gamma glutamyltranspeptidase 1 | |
| Gamma-glutamyltransferase 1 | |
| Gamma-glutamyltranspeptidase 1 light chain | |
| GGT 1 | |
| GGT | |
| GGT1 | |
| GGT1_HUMAN | |
| Glutamyl transpeptidase |
Target information
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Provider
Erpantech Laboratory
