Anti-Galectin 8 antibody
Specifications
| Product Cat#: | AB-06-1831 |
| Product type: | Primary antibody |
| Antigen: | Galectin 8 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:400-1:800); Immunofluorescence(1:400-1:800); Flow Cytometry (1:50-1:100); Immunoprecipitation |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JB85-35) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | Gal 8 antibody |
| Gal-8 antibody | |
| Gal8 antibody | |
| Galectin-8 antibody | |
| galectin-8g antibody | |
| Lectin galactoside binding soluble 8 antibody | |
| LEG8_HUMAN antibody | |
| LGAL S8 antibody | |
| Lgals8 antibody | |
| PCTA 1 antibody | |
| PCTA-1 antibody | |
| PCTA1 antibody | |
| Po66 carbohydrate binding protein antibody | |
| Po66 carbohydrate-binding protein antibody | |
| Po66 CBP antibody | |
| Po66-CBP antibody | |
| Prostate carcinoma tumor antigen 1 antibody |
Target information
Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3′-O-sialylated and 3′-O-sulfated glycans (PubMed:21288902).
Provider
Erpantech Laboratory
