Anti-GABRA2 antibody
Specifications
| Product Cat#: | AB-06-1819 |
| Product type: | Primary antibody |
| Antigen: | GABRA2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human GABRA2/GABA A Receptor alpha 2 185-280/451 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1μg/Test); Immunohistochemistry-Paraffin (1:400-1:800) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | GABA A Receptor a2 |
| GABA A Receptor alpha 2 | |
| GABA A receptor subunit alpha 2 | |
| GABA | |
| GABA(A) receptor subunit alpha 2 | |
| GABA(A) receptor subunit alpha-2 | |
| GABR A2 | |
| GABRA 2 | |
| GABRA2 | |
| GABRA2 protein | |
| Gamma aminobutyric acid (GABA) A receptor alpha 2 | |
| Gamma aminobutyric acid A receptor alpha 2 | |
| Gamma aminobutyric acid receptor alpha 2 subunit | |
| Gamma aminobutyric acid receptor subunit alpha 2 | |
| Gamma-aminobutyric acid receptor subunit alpha-2 |
Target information
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha2/beta2/gamma2 receptor exhibits synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).
Provider
Erpantech Laboratory
