Anti-FUSIP1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | FUSIP1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human FUSIP1 151-250/262 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 40 kDa SR repressor protein |
| 40 kDa SR-repressor protein | |
| Anti TLS associated protein with SR repeats | |
| Arginine/serine-rich 13A | |
| FUS interacting protein serine arginine rich 1 | |
| FUS interacting protein serine arginine rich 2 | |
| FUS interacting serine arginine rich protein 1 | |
| FUS-interacting serine-arginine-rich protein 1 | |
| FUSIP1 | |
| FUSIP2 | |
| NSSR | |
| OTTHUMP00000015774 | |
| Serine arginine repressor protein 40 kDa | |
| Serine/arginine-rich splicing factor 10 | |
| SFRS13 | |
| SFRS13A | |
| Splicing factor | |
| Splicing factor arginine serine rich 13 | |
| Splicing factor SRp38 | |
| SRp38 | |
| SRp40 | |
| SRrp40 | |
| SRS10_HUMAN | |
| Srsf10 | |
| TASR | |
| TASR1 | |
| TASR2 | |
| TLS associated protein TASR1 | |
| TLS associated protein TASR2 | |
| TLS associated protein with Ser Arg repeats | |
| TLS associated protein with SR repeats | |
| TLS associated serine arginine protein 1 | |
| TLS associated serine arginine protein 2 | |
| TLS associated serine arginine protein | |
| TLS associated SR protein | |
| TLS-associated protein with Ser-Arg repeats | |
| TLS-associated protein with SR repeats | |
| TLS-associated serine-arginine protein |
Target information
Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing . Seems to interfere with the U1 snRNP 5′-splice recognition of SNRNP70 . Required for splicing repression in M-phase cells and after heat shock. Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing . May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator .
Provider
Erpantech Laboratory
