Anti-Frizzled 10/CD350 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Frizzled 10/CD350 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Frizzled 10/CD350 101-200/581 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 350 |
| CD 350 antigen | |
| CD350 | |
| Frizzled (Drosophila) homolog 10 | |
| Frizzled-10 | |
| FZ 10 | |
| Fz-10 | |
| FZ10 | |
| FZD 10 | |
| FZD10 | |
| FZD10_HUMAN | |
| FzE 7 | |
| FzE7 | |
| HFz 10 |
Target information
Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
Provider
Erpantech Laboratory
