Anti-Filamin-A antibody
Specifications
| Product Cat#: | AB-06-1728 |
| Product type: | Primary antibody |
| Antigen: | Filamin-A |
| Immunogen: | Recombinant protein. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:2000); Immunocytochemistry (1:200); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:200) |
| Reactivity: | Human,mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA; 40% glycerol, 0.05% NaN 3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ABP 280 antibody |
| ABP-280 antibody | |
| Actin-binding protein 280 antibody | |
| Alpha filamin antibody | |
| Alpha-filamin antibody | |
| APBX antibody | |
| CSBS antibody | |
| CVD1 antibody | |
| Endothelial actin binding protein antibody | |
| Endothelial actin-binding protein antibody | |
| Filamin 1 antibody | |
| Filamin A alpha antibody | |
| Filamin A antibody | |
| Filamin-1 antibody | |
| Filamin-A antibody | |
| FLN antibody | |
| FLN-A antibody | |
| FLN1 antibody | |
| FLNA antibody | |
| FLNA_HUMAN antibody | |
| FMD antibody | |
| MNS antibody | |
| NHBP antibody | |
| Non muscle filamin antibody | |
| Non-muscle filamin antibody | |
| OPD antibody | |
| OPD1 antibody | |
| OPD2 antibody | |
| XLVD antibody | |
| XMVD antibody |
Target information
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).
Provider
Erpantech Laboratory
