Anti-Fibrinogen gamma chain antibody
Specifications
| Product Cat#: | AB-06-1721 |
| Product type: | Primary antibody |
| Antigen: | Fibrinogen gamma chain |
| Immunogen: | Recombinant protein corresponding to human Fibrinogen gamma 50-250aa. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:4500-1:10000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal, JG37-18 |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1% BSA; 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FGG antibody |
| FIBG_HUMAN antibody | |
| Fibrinogen gamma chain antibody | |
| Fibrinogen gamma polypeptide antibody |
Target information
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Provider
Erpantech Laboratory
