Anti-Fibrillarin antibody
Specifications
| Product Cat#: | AB-06-1716 |
| Product type: | Primary antibody |
| Antigen: | Fibrillarin |
| Immunogen: | Synthetic peptide of C-terminal human Fibrillarin. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Flow Cytometry (1:50-1:200) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 0.5% BSA; 50% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 34 kD nucleolar scleroderma antigen antibody |
| 34 kDa nucleolar scleroderma antigen antibody | |
| Fbl antibody | |
| FBRL_HUMAN antibody | |
| FIB antibody | |
| FIB1 antibody | |
| FLRN antibody | |
| Histone-glutamine methyltransferase antibody | |
| Nop1p antibody | |
| RNA U3 small nucleolar interacting protein 1 antibody | |
| RNU3IP1 antibody | |
| RRNA 2' O methyltransferase fibrillarin antibody | |
| RRNA 2'-O-methyltransferase fibrillarin antibody |
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Target information
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2′-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of ‘Gln-105’ of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus.
Provider
Erpantech Laboratory
